KUBÁSEK Jiří VŠCHT v Praze

Spoluautoři VOJTĚCH Dalibor

Magnesium is an essential element for human organism that works as a cofactor for some enzymes, participates in DNA or RNA synthesis and support bone growth. Mechanical properties, such as density and modulus of elasticity, are close to that of bones. Therefore, magnesium is suitable element for manufacture of biodegradable implants. Compared to currently used non-degradable Ti- based or Co-Cr-based implants and steel implants, these materials are gradually dissolved in organism. As a consequence, no second surgery for implant removal is needed. The main insufficiency of Mg and Mg-based alloys is especially still too high corrosion rate, which mean that Mg-based implant are degraded or lose necessary mechanical properties in human organism before the tissue is sufficiently healed. Different methods has been used to increase corrosion resistance in body fluid, such suitable alloying especially by Rare Earth Elements (REE), modification of structure by mechanical or thermal treatment, different surface treatment or preparation of composites. In this study, influence of thermal and mechanical treatment on mechanical and corrosion properties of pure magnesium, AZ31 and WE43 magnesium alloys were studied. Both alloys are considered as candidates for production of implant materials. Studied alloys were characterized by significantly improved mechanical properties and corrosion resistance compared to pure magnesium in the as-cast state and these properties were further influenced by condition of extrusion process or thermal treatment. WE43 alloy seems as the most prospective material for medical applications.

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